Several human studies on consumption of mango (Mangifera indica) have found multiple health benefits associated with the fruit including improved blood pressure, blood sugar control, and gut health. The findings were published recently in the FASEB Journal and presented at the 2017 Experimental Biology Conference.
“This emerging research shows promising outcomes on mango’s potential to reduce the risk of metabolic disorders and chronic inflammation,” said Leonardo Ortega, Director of Research at the National Mango Board.
The research was carried out by scientists from Texas AM University and Oklahoma State University.
In one of the studies, Dr. Susanne Mertens-Talcott, associate professor in the Department of Nutrition and Food Science at Texas AM University, and co-authors examined the absorption, metabolism, and excretion of gallic acid, galloyl glycosides, and gallotannins in lean and obese individuals that consumed 400 g of freshly frozen mango pulp daily for six weeks.
“Extended mango consumption may offer increased anti-inflammatory benefits compared to sporadic mango consumption and this would need to be confirmed within an extended efficacy study,” Dr. Mertens-Talcott said.
In a randomized pilot study, Texas AM University postdoctoral researcher Dr. Hyemee Kim and colleagues investigated the potential role of mango consumption in changes of the gut microbiota, bioavailability of galloyl metabolites, and anti-inflammatory activities in lean and obese subjects.
In a separate study, Texas AM University scientist Dr. Chuo Fang and co-authors investigated the metabolic effects of daily consumption of freshly frozen mango pulp (400 g) for six weeks in lean and obese subjects and the relationship between mango metabolites to Body Mass Index (BMI) and circulating biomarkers.
“Daily mango consumption lowers blood pressure in lean individuals, and benefits obese individuals by maintaining long-term glucose homeostasis,” the researchers concluded.
“Galloyl-derivatives from mango may possess therapeutic potential in the prevention and treatment of obesity and metabolic disorders, which remain to be confirmed in a larger-size human clinical trial.”
Oklahoma State University researcher Crystal O’Hara and colleagues examined the post-prandial response of young, healthy males (18-25 years) following consumption of a typical American high-fat breakfast with or without a mango shake, which included 50 g of mango pulp (equivalent to 250 g of fresh mango).
“Acute mango consumption had modest effects on post-prandial responses,” the authors said.
Susanne U Mertens-Talcott et al. 2017. Adaptation of Galloyl Derivatives Metabolism and Excretion After 42 Days of Mango (Mangifera indica L.) Consumption. The FASEB Journal 31 (1): supplement 646.14
Hyemee Kim et al. 2017. Intestinal Microbiota and Host Metabolism Respond Differentially in Lean and Obese Individuals Following Six-Week Consumption of Galloyl Derivatives from Mango (Mangifera indica L.) Pulp. The FASEB Journal 31 (1): supplement 166.8
Chuo Fang et al. 2017. Daily Mango (Mangifera indica L.) Consumption for 42 Days Differentially Modulates Metabolism and Inflammation in Lean and Obese Individuals. The FASEB Journal 31 (1): supplement 431.3
Crystal O’Hara et al. 2017. The Effects of Acute Freeze-Dried Mango Consumption with a High-Fat Meal on Post-Prandial Responses in Healthy Young Adult Males. The FASEB Journal 31 (1): supplement 166.3